Scientist, CNS Pharmacology
Scientist, CNS Pharmacology
HQ- Cambridge, MA / R&D- CNS / Salaried, full-time / On-site The CNS Team at Arbor Biotechnologies is looking for a Scientist interested in functioning at the cross section of technology and therapeutics. Our team is leveraging the strength of Arbor’s discovery capabilities to advance the challenging field of CNS therapeutics by utilizing patient-derived CNS cell types, humanized mouse models and nonhuman primate. Arbor is a highly collaborative environment, and you will have the opportunity to work closely with the discovery, computation, and protein engineering teams, as well as to continue to explore new techniques for your professional growth. This role is at the forefront of Arbor’s translational evolution and will be given an opportunity to solidify the understanding of our assets for internal and external therapeutic development. We seek highly motivated individuals with the dedication, integrity, and creative spirit needed to thrive in an innovative company. Working at Arbor offers a unique opportunity that combines the fast pace and growth opportunities of a startup with the intellectual rigor and creativity of academia. Key Responsibilities
Designing experiments to validate gene-editing technology in animal models to show successful and efficient gene-editing and reversal of disease-relevant phenotypes, when applicable.
Interacting and collaborating with delivery group to optimize the delivery of gene editor into the CNS space.
Interacting and collaborating with analytics group to optimize the biomarkers and analytical assays for monitoring gene-editing outcome in vivo and toward clinical application.
Planning and executing (if applicable) experiments, and processing/analyzing data independently.
Manage CROs, interpret and communicate data across functions, and predict timelines and deliverables to internal and external stakeholders.
Education: Ph.D. in neuroscience, cell biology, molecular biology, biochemistry, or relevant field and a minimum of 0-2 years related experience; may include post-doctoral experience.
Experience in CNS tissue harvesting, processing and downstream cellular/molecular/biochemical analysis.
Experience in animal models of CNS diseases
Experience in AAV-mediated gene delivery in vivo
Knowledge of the biological, genetic and molecular basis of CNS diseases
Attention to details and excellent organizational skills, ensuring good documentation practices are used to maintain record of work being performed.
Highly versatile and team-based mindset
Excellent verbal, written communication and presentation skills are essential
Our Values:Our values govern the work we do at Arbor, and we’re hoping that they resonate as strongly with you as they do with us! · Purposeful Action: Start with The Why · Bold Resilience: Adopt a Growth Mindset · Humble Authenticity: Start in the Heart About Arbor:At Arbor, we are discovering, developing and making available to all patients the next-generation of genetic medicines. We are disrupting the field through our proprietary discovery engine to develop a portfolio of differentiated genetic editing and delivery capabilities. We have an unencumbered portfolio of multiple CRISPR based genetic modifiers that can be tailored to correct the underlying pathology of each genetic disease. Our pipeline of genetic medicines will focus on bringing cures to all patients with genetic disease. We seek highly-motivated individuals with the dedication, integrity, and creative spirit needed to thrive in an innovative company. Working at Arbor offers a unique opportunity that combines the fast pace and growth opportunities of a startup with the intellectual rigor and creativity of academia. Our salaries are competitive, our benefits are generous, and our team is exceptional. Arbor Biotechnologies is proud to be an inclusive workplace and an Equal Opportunity Employer.